If you can’t find what you need, contact us to solve your problems. Capto SP ImpRes ion exchange chromatography resin.
Scaling up allows for high resolution combined with quick flow rates.
Help us improve your experience by sending an error report. We are currently inpres our website.īy imprez the high-flow characteristics of Capto resin with a small particle size, Capto SP ImpRes delivers excellent pressure-flow properties with impressive resolution. Process development scale - prepacked PreDictor Capto SP ImpRes filter plates - well plates for high-throughput screening or process development. HiTrap Capto SP ImpRes cation exchange chromatography column – GE Healthcare Life Sciences Be the first to leave a dp The ability to run at higher flow rates and higher bed heights also increases flexibility in process design. Process-scale purification - prepacked ReadyToProcess Capto SP ImpRes columns - 1 L and larger columns for clinical manufacturing that avoid the need for cleaning and cleaning validation.
Capto MMC ImpRes, and Capto adhere ImpRes media in large-scale chromatography columns. verified bed stability for Capto SP ImpRes, Capto Q ImpRes. This product is no longer available on Biocompare. Capto SP ImpRes, mL from GE Healthcare Life Sciences. Biophys Chem 127:1–8īurgess RR (2018) A brief practical review of size exclusion chromatography: rules of thumb, limitations, and troubleshooting.Capto™ SP ImpRes GE Healthcare,, pack of 25 mL find Sigma- GE MSDS, related peer-reviewed papers, technical documents, similar. Data file 29-0356-74 ABĪrakawa T, Ejima D, Tsumoto K, Obeyama N, Tanaka Y, Kita Y, Timasheff SN (2007) Suppression of protein interactions by arginine: a proposed mechanism of the arginine effects. GE Healthcare Life Sciences (2015) Capto™ MMC ImpRes. GE Healthcare Life Sciences (2013) Polishing of monoclonal antibodies using Capto™ MMC ImpRes in bind and elute mode. J Chromatogr A 1294:70–75Ĭhmielowski RA, Meissner S, Roush D, Linden TO, Glowacki E, Konietzko J, Nti-Gyabaah J (2014) Resolution of heterogeneous charged antibody aggregates via multimodal chromatography: a comparison to conventional approaches. Gao D, Wang LL, Lin DQ, Yao SJ (2013) Evaluating antibody monomer separation from associated aggregates using mixed-mode chromatography. Bioprocess Int 7:52–56Ĭhen J, Tetrault J, Zhang Y, Wasserman A, Conley G, Dileo M, Haimes E, Nixon AE, Ley A (2010) The distinctive separation attributes of mixed-mode resins and their application in monoclonal antibody downstream purification process. Curr Pharm Biotechnol 10:440–446Įriksson K, Ljunglöf A, Rodrigo G, Brekkan E (2009) MAb contaminant removal with a multimodal anion exchanger: a platform step to follow protein A. Gagnon P, Beam K (2009) Antibody aggregate removal by hydroxyapatite chromatography. Gagnon P, Ng P, Aberrin C, Zhen J, He J, Mekosh H, Cummings L, Richieri R, Zaidi S (2006) A ceramic hydroxyapatite based purification platform: simultaneous removal of leached protein A, aggregates, DNA, and endotoxins. McCue JT (2009) Theory and use of hydrophobic interaction chromatography in protein purification applications. Lu Y, Williamson B, Gillespie R (2009) Recent advancement in application of hydrophobic interaction chromatography for aggregate removal in industrial purification process. McCue JT, Engel P, Ng A, Macniven R, Thömmes J (2008) Modeling of protein monomer/aggregate purification and separation using hydrophobic interaction chromatography. Zhang X, Chen T, Li Y (2019) A parallel demonstration of different resins' antibody aggregate removing capability by a case study. He X (2015) Mixed-mode chromatography for mAb S aggregate removal: comparison of CHT™ ceramic hydroxyapatite, capto adhere, and capto adhere impres. Hall T, Wilson JJ, Brownlee TJ, Swartling JR, Langan SE, Lambooy PK (2015) Alkaline cation-exchange chromatography for the reduction of aggregate and a mis-formed disulfide variant in a bispecific antibody purification process. Vázquez-Rey M, Lang DA (2011) Aggregates in monoclonal antibody manufacturing processes. Bonnerjea J, Brake RP, Davis MR, Kellerman K, Preneta A (2008) Ion exchange chromatography and purification of antibodies, United States patent application publication US 2008/0312425 A1
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